A team led by HHMI Hanna Gray Fellow Shan Meltzer has created a detailed, cell-by-cell map of the spinal cord that offers a new framework for understanding chronic pain and provides a powerful new ...

Touch—the first sense to develop in the womb—is fundamental to our bodily experience and our everyday lives. Yet, as the least studied of the five senses, it remains somewhat mysterious at the ...

Diabetic macrovascular complications are the main cause of death and disability in diabetes patients, of which vascular calcification is one of the key pathological mechanisms. Calcification in ...

Explore how proteomics in biomarker discovery accelerates diagnostic assay development and improves clinical validation.

Single-cell omics is a transformative area within life sciences, enabling researchers to untangle cellular heterogeneity, uncover developmental lineages, ...

Recent advancements in systems biology have been propelled by the increasing power of omics technologies—spanning genomics, transcriptomics, proteomics, ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

Explore how clinical multi-omics integration drives systems medicine, detailing data fusion methodologies and lab ...

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

AGBT is also, increasingly, a showcase for instruments for spatial biology, a fast-growing field that involves pinpointing the location of RNA and protein molecules en masse. Tarbox calls the meeting ...

This important work identifies phlda2 as a specific marker for primordial cardiomyocytes in the adult zebrafish heart and demonstrates their essential role in myocardial morphogenesis and coronary ...