A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded ...

A team at ETH Zurich developed a new peptide-based organocatalyst that handles macrocycle formation from start to finish.

The protein factories in our cells – so-called ribosomes – have a central task: during a process known as translation, amino acids are linked together according to messenger RNA, forming a growing ...

Video - Compilation of protein condensate formation. Full video available from Supplementary Information of the original article .

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...