A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

Scientists show that endocrine stem cells in the pancreas disappear after birth, and detail the genetic identity of the different types of pancreatic hormone-producing cells. The pancreas is a key ...

Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study.

During embryonic stem cell (ESC) development, pluripotent stem cells transition from a naïve state into a primed state before they take their first steps toward a lineage commitment. Jacob Hanna, a ...

Scientists have grown a scalable new embryo-like model that unshrouds some mysteries of early human development, including blood cell formation, or hematopoiesis—a first for the field. In an article ...

Scientists are using human stem cells to create a structure that mimics a pre-embryo and can serve as a research alternative to a real one. They say these “blastoids” provide an efficient, ethical way ...