There are two types of herpes simplex virus, type 1 and type 2 (HSV-1 and HSV-2), both belong to the Herpesviridae family, Alphaherpesvirinae subfamily. Herpes simplex virus type 2 is a common human ...
To create an oncolytic herpes simplex virus type 1 (HSV-1) that is inhibited for reactivation, we constructed a novel herpes recombinant virus with deletions in the γ34.5 and LAT genes. The LAT gene ...
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